【每周一问】2023.12.18-关于毛囊组织病理切片（第1问）

王帆

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请为以下6张毛囊的病理组织切片照片，找到对应的文字描述？

1：生长期毛囊球上横截面；

2：毛球上部横截面；

3：毛囊漏斗部横截面；

4：毛球下部横截面；

5：生长期毛囊峡部横截面；

6：静止期毛囊峡部横截面；

答案揭晓：

a-f六张图片是毛囊(HF)不同水平截面的切片。

(a)HF漏斗部的横截面。漏斗壁由黑箭所示。毛囊腔内充满了数个毛干(HS)和漏斗部角蛋白。观察漏斗部不能确定毛发的周期阶段。

(b)生长期HF峡部横截面。HS由最内层的髓质、皮质和薄的毛小皮层组成。它由完全角化的内根鞘(箭头)、伴行层(不可见)、外根鞘(沙漏)和纤维鞘(黑边白箭)包围。

(c)生长期毛囊的球上区横截面。请注意，内根鞘的Henle层已完全角化，而Huxley层尚未角化，与HS髓质中尚未角化的毛细胞一样，其特征是存在毛透明蛋白颗粒。白箭指示伴行层的细胞。

(d)毛球上部的横截面。真皮乳头(星形)被基质细胞(黑色圆圈)包围，基质细胞又被纤维鞘(黑边白箭)包围。

(e)毛球下部的横截面。

(f)静止期HF峡部的横截面。棒状毛由外根鞘的毛膜角蛋白锚定，外根鞘由纤维鞘包围。

苏木精-伊红染色。HS：毛干。

Horizontal sections through the different segments of the hair follicle (HF).

(a) Cross section through an infundibulum. The infundibular wall is indicated by the black arrow. The lumen is filled with several hair shafts (HS) and infundibular keratin. The hair cycle stage cannot be determined looking at the infundibulum.

(b) Cross section through the isthmus of an anagen HF. The HS is composed of the innermost medulla, the cortex, and the thin cuticle. It is surrounded by a fully cornified inner root sheath (arrowhead), the companion layer (not visible), the outer root sheath (hourglass), and the fibrous sheath (white arrow surrounded by black).

(c) Cross section through the suprabulbar region of an anagen follicle. Note that the Henle layer of the inner root sheath is fully cornified whereas the Huxley layer is not yet cornified and is, like the not yet cornified trichocytes of the HS medulla, characterized by the presence of trichohyalin granules. The white arrow indicates the cells of the companion layer.

(d) Cross section through the upper part of the hair bulb. The dermal papilla (star) is surrounded by matrix cells (black circle) which are in turn surrounded by the fibrous sheath (white arrow surrounded by black).

(e) Cross section through the lower portion of the hair bulb.

(f) Cross section through the isthmus of a telogen HF. The club hair is anchored by trichilemmal keratin to the outer root sheath, which is in turn surrounded by a fibrous sheath.

Hematoxylin and eosin. HS, hair shaft.

所以依次对应是：a-3；b-5；c-1；d-2；e-4；f-6

你答对了吗？

Urumqi冬

a3b2c4d5e6f1，期待正确答案

袁丽娟

a3 b5 c1 d4 e2 f6

刘双元

1a 2b 3f 4c 5d 6e

vetwei

1a 2b 3f 4c 5d 6e